Pharmacokinetics of Chitobiose and Chitotriose Administered Intravenously or Orally to Rats

Chitooligosaccharides have attracted much attention as new biomedical materials. The biologic availability of each of these chitooligosaccharides, however, has not yet been studied. In the present study, we found that chitobiose and chitotriose appeared in the blood of rats with maximum plasma conce...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2005, Vol.28(3), pp.545-548
Hauptverfasser:	Chen, An-Shu, Taguchi, Tadao, Okamoto, Hirokazu, Danjo, Kazumi, Sakai, Kazuo, Matahira, Yoshiharu, Wang, Min-Wei, Miwa, Ichitomo
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals chitobiose chitooligosaccharide chitotriose Disaccharides - administration & dosage Disaccharides - pharmacokinetics Dose-Response Relationship, Drug Injections, Intravenous Male pharmacokinetic Rats Rats, Wistar Trisaccharides - administration & dosage Trisaccharides - pharmacokinetics
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