Clinical Efficacy of Therapeutic Drug Monitoring in Patients Receiving Vancomycin

Efficacy of therapeutic drug monitoring (TDM) of vancomycin (VCM) was retrospectively investigated in 184 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. The incidence of nephrotoxicity was compared between the patients who received TDM practice (TDM group, n=73) and did...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2003, Vol.26(6), pp.876-879
Hauptverfasser:	Iwamoto, Takuya, Kagawa, Yoshiyuki, Kojima, Michio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - blood Anti-Bacterial Agents - therapeutic use Biological and medical sciences Child Child, Preschool Drug Monitoring Drug Utilization - trends efficacy Female Humans Infant Infusions, Intravenous Male Medical sciences Methicillin Resistance methicillin-resistant Staphylococcus aureus (MRSA) Middle Aged nephrotoxicity Retrospective Studies Staphylococcal Infections - drug therapy Staphylococcus aureus - drug effects therapeutic drug monitoring vancomycin Vancomycin - administration & dosage Vancomycin - blood Vancomycin - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Efficacy of therapeutic drug monitoring (TDM) of vancomycin (VCM) was retrospectively investigated in 184 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. The incidence of nephrotoxicity was compared between the patients who received TDM practice (TDM group, n=73) and did not (non-TDM group, n=111). Creatinine clearance (CLcr) values decreased significantly after the VCM therapy in the non-TDM group (p
ISSN:	0918-6158 1347-5215
DOI:	10.1248/bpb.26.876