Enzymatic activity, slime production and antifungal agent sensitivity of Candida sp

Abilith of Candida spp to secrete extracellular enzymes and slime has been associated as pathogenicity factors. Out of a total of 37 strains of Candida sp, 100% were proteinase producers, 83.8% were phospholipase producers, 64.9% were slime producers and 100% were sensitive to fluconazole and itraco...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Revista da Sociedade Brasileira de Medicina Tropical 2007-05, Vol.40 (3), p.354
Hauptverfasser:	Silva, Jaqueline Otero, Ferreira, Joseane Cristina, Candido, Regina Célia
Format:	Artikel
Sprache:	eng ; por
Schlagworte:	Antifungal Agents - pharmacology Biofilms - drug effects Biofilms - growth & development Candida - drug effects Candida - enzymology Candida - physiology Enzymatic activity Fluconazole - pharmacology Humans Itraconazole - pharmacology Microbial Sensitivity Tests Pathogens Peptide Hydrolases - drug effects Peptide Hydrolases - metabolism Phospholipases - drug effects Phospholipases - metabolism Slime Yeasts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Abilith of Candida spp to secrete extracellular enzymes and slime has been associated as pathogenicity factors. Out of a total of 37 strains of Candida sp, 100% were proteinase producers, 83.8% were phospholipase producers, 64.9% were slime producers and 100% were sensitive to fluconazole and itraconazole. Seventeen typings (enzymes/slime) were found. This methodology presented a good discrimination rate (D=0.93) and could be used for phenotypic characterization of yeasts.
ISSN:	0037-8682 1678-9849
DOI:	10.1590/S0037-86822007000300023