Biotransformation of Paclitaxel by Cell Suspension Cultures of Marchantia polymorpha
Biotransformation of paclitaxel by cell suspension cultures of Marchantia polymorpha was studied and it was found that liverwort cultures convert paclitaxel to 7-epi-paclitaxel in good yield and regioselectively hydrolyses the ester group at the 10-position of paclitaxel.
Gespeichert in:
| Veröffentlicht in: | Plant Biotechnology 2000/12/01, Vol.17(4), pp.321-323 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Biotransformation of paclitaxel by cell suspension cultures of Marchantia polymorpha was studied and it was found that liverwort cultures convert paclitaxel to 7-epi-paclitaxel in good yield and regioselectively hydrolyses the ester group at the 10-position of paclitaxel. |
|---|---|
| ISSN: | 1342-4580 1347-6114 |
| DOI: | 10.5511/plantbiotechnology.17.321 |