ADULT CYSTIC FIBROSIS VITAMIN D AND BONE MINERAL DENSITY AUDIT

Up to 90% of individuals with Cystic Fibrosis (CF) are pancreatic insufficient. This can lead to fat malabsorption. Fat soluble vitamins are co-absorbed with fat and thus deficiencies may occur. Vitamin D deficiency is common in individuals with CF. Vitamin D deficiency has been related to decreased bone mineral density, osteopenia and poorer general and respiratory health in adults with CF. It is vital that there is continued monitoring of Vitamin D status in CF patients. Audit the Vitamin D status and most recent bone mineral density (DXA) result of all patients (n = 54) cared for by the Canterbury Adult CF Service (CACFS) to consider if current supplementation processes are adequate. Cross-sectional survey. Vitamin D status assessed via Plasma 25 Hydroxy Vitamin D (Vitamin D). Descriptive statistics calculated. 18% (n = 10) of patients had a Vitamin D result 50 but 75 nmol/L (optimal). For patients with an available DXA scan (83%, n = 45), 71% (n = 32) had normal bone mass, 7% (n = 5) had low bone mass, 11% (n = 5) had osteopenia, and 7% (n = 3) osteoporosis. Of those patients with osteopenia (n = 5), one had a Vitamin D 50 nmol/L but 75 nmol/L. All patients with osteoporosis (n = 3) had a Vitamin D >75 nmol/L. The majority of patients cared for by the CACFS have a satisfactory Vitamin D status and bone mineral density; however 46% of patients potentially require more intense vitamin D intervention.