Effects of Extracts from GOISHICHA on Serum and Liver Lipid Concentrations in Rats

A substance, extracted from GOISHICHA in water and ethyl alcohol (ethanol) was administered to rats for 3 weeks (both extracts were each dissolved in distilled water to adjust concentration to 100 mg/ml/day, and administered orally using a gastric tube) and the animals were examined for the effects on serum and liver lipids. 1) TC concentration was considerably suppressed by both extracts which also enhanced HDL-C. 2) PL significantly increased by the water extract while the ethanol extract increased PL though not significantly. 3) Both extracts significantly suppressed LOOH thus confirming the antioxidant effect of each. 4) TL content was basically the same for the two experimental groups the ethanol extract having pronounced effect on TC and FFA, and PL content and the water extract,only on that of TG.