Cosmetic Substance Synthesis from Estragole Derivatives for Skin Depigmentation

Natural material extracts are presently used as cosmetic ingredients. Their physiological effects were examined using estragole isolated from the essential oil of Foeniculum vulgare Miller as starting materials. Thirty derivatives were synthesized by condensation using ten thiols. The derivatives were examined for potential use as whitening agents possessing tyrosinase activity and superoxide dismutase. Derivative compounds were found good inhibitors of tyrosinase.