Identification Tests of Aristolochic Acid in Crude Drugs by Reversed-Phase TLC/Scanning Densitometry

Identification Tests of Aristolochic Acid in Crude Drugs by Reversed-Phase TLC/Scanning Densitometry

We performed identification tests of aristolochic acid in Xixin, Mutong, Muxiang, and Fangji by reversed-phase TLC/scanning densitometry using aristolochic acid I as a marker compound. The developing solvents used were: I) acetonitrile/methanol/water mixture solution (3 : 1 : 1) and II) 2-butanone/m...

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Veröffentlicht in:Journal of Health Science 2006, Vol.52(1), pp.78-81
Hauptverfasser: Ohno, Tsutomu, Mikami, Eiichi, Matsumoto, Hiroshi, Kawaguchi, Naoki
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aristolochic acid
reversed-phase TLC
scanning densitometry
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container_title Journal of Health Science
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creator Ohno, Tsutomu
Mikami, Eiichi
Matsumoto, Hiroshi
Kawaguchi, Naoki
description We performed identification tests of aristolochic acid in Xixin, Mutong, Muxiang, and Fangji by reversed-phase TLC/scanning densitometry using aristolochic acid I as a marker compound. The developing solvents used were: I) acetonitrile/methanol/water mixture solution (3 : 1 : 1) and II) 2-butanone/methanol/sodium sulfate(1→20) mixture solution (2 : 1 : 1). The Rf value of aristolochic acid I was 0.54 using the I system and 0.57 using the II system. The maximum absorption wavelengths of aristolochic acid I observed by scanning densitometry were 254 and 325 nm.
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reversed-phase TLC
scanning densitometry
title Identification Tests of Aristolochic Acid in Crude Drugs by Reversed-Phase TLC/Scanning Densitometry
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