Antihypertensive Effect of Extracts of Lactobacillus casei in Patients with Hypertension

An extract of autologous Lactobacillus casei cell lysate (LEx) is known to lower the blood pressure of spontaneously hypertensive rats (SHR). To determine the effects of LEx in humans, we enrolled twenty-eight patients with an average age of seventy-one years and with an average systolic blood press...

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Veröffentlicht in:Journal of Clinical Biochemistry and Nutrition 1995, Vol.18(3), pp.181-187
Hauptverfasser: NAKAJIMA, Kumiko, HATA, Yoshiya, OSONO, Yasunori, HAMURA, Mahoko, KOBAYASHI, Seizaburo, WATANUKI, Masaaki
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Sprache:eng
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Zusammenfassung:An extract of autologous Lactobacillus casei cell lysate (LEx) is known to lower the blood pressure of spontaneously hypertensive rats (SHR). To determine the effects of LEx in humans, we enrolled twenty-eight patients with an average age of seventy-one years and with an average systolic blood pressure/diastolic blood pressure of 164/96mmHg in a 2-month, double-blind, placebo-controlled study. Four hundred milligrams of LEx or placebo powder enclosed in white capsules was given twice a day for 2 months. Decreases in systolic blood pressure (p
ISSN:0912-0009
1880-5086
DOI:10.3164/jcbn.18.181