ChemInform Abstract: A Practical, Ligand-Free, Palladium-Catalyzed Isocyanide Insertion Reaction for the Construction of Novel Ring-Fused Quinazolines

ChemInform Abstract: A Practical, Ligand-Free, Palladium-Catalyzed Isocyanide Insertion Reaction for the Construction of Novel Ring-Fused Quinazolines

A cascade reaction of isatoic anhydride, phenylhydrazines and 2‐bromobenzaldehyde provides the key intermediates (IV) which undergo Pd‐catalyzed isocyanide insertion reactions to afford novel ring‐fused quinazolines.

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Veröffentlicht in:ChemInform 2013-10, Vol.44 (44), p.no-no
Hauptverfasser: Ji, Fei, Lv, Mei-fang, Yi, Wen-bin, Cai, Chun
Format: Artikel
Sprache:eng
Schlagworte:
C-C bond formation
fused pyrimidine derivatives
multicomponent reactions
ring closure reactions
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Zusammenfassung:A cascade reaction of isatoic anhydride, phenylhydrazines and 2‐bromobenzaldehyde provides the key intermediates (IV) which undergo Pd‐catalyzed isocyanide insertion reactions to afford novel ring‐fused quinazolines.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201344169