ChemInform Abstract: The Heterocyclic Ring of 4-Substituted-1,8-naphthalimides is NOT Inert to Nucleophilic Attack, Contrary to Earlier Reports

ChemInform Abstract: The Heterocyclic Ring of 4-Substituted-1,8-naphthalimides is NOT Inert to Nucleophilic Attack, Contrary to Earlier Reports

The heterocyclic ring of title compounds (I) and (IV), reported to be resistant to nucleophilic attack, reacts with primary amine nucleophiles at room temperature to the corresponding N‐alkyl derivatives (IV) and (VII), respectively (yield not given in part).

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Bibliographische Detailangaben
Veröffentlicht in:ChemInform 2013-10, Vol.44 (41), p.no-no
Hauptverfasser: McKenney, Ryan K., Groess, Leah L., Kopidlansky, Kyle M., Dunkle, Kelsey L., Lewis, David E.
Format: Artikel
Sprache:eng
Schlagworte:
amination
amination, N‐alkylation, N‐arylation
carboxylic acid derivatives (naphthalene compounds)
N-alkylation
N-arylation
substitution reactions
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Beschreibung
Zusammenfassung:The heterocyclic ring of title compounds (I) and (IV), reported to be resistant to nucleophilic attack, reacts with primary amine nucleophiles at room temperature to the corresponding N‐alkyl derivatives (IV) and (VII), respectively (yield not given in part).
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201341086