Addressing Ethical, Social, and Cultural Issues in Global Health Research: e2227

Since first proposed [2], there has been some attention to the evolution of CSREs in the literature [3], [4], with much of the focus on how to achieve an appropriate balance between the advisory/consulting role of the emerging CSREs and the review, monitoring, and oversight responsibilities of their counterpart institutional review boards (IRBs) [5]. [...]the importance of integration, of looking for broad applications of narrowly intended solutions, of bringing diverse perspectives to bear on complex ethical challenges, and of rigorous impact evaluation are by no means limited to global health; as such, we hope these lessons may also prove useful for CSREs focused on a wide range of scientific endeavors.