Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer

Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer

Background: Breast cancer is associated with a relatively good prognosis. Prognostic factors examined to date are related to early recurrence while those related to late recurrence and their countermeasures remain unclear. Therefore, we examined the factors related to late recurrence. Patients and M...

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Veröffentlicht in:Oncology 2013-01, Vol.85 (2), p.100-110
Hauptverfasser: Nishimura, Reiki, Osako, Tomofumi, Nishiyama, Yasuyuki, Tashima, Rumiko, Nakano, Masahiro, Fujisue, Mamiko, Toyozumi, Yasuo, Arima, Nobuyuki
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Breast cancer
Breast Neoplasms - metabolism
Breast Neoplasms - mortality
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Clinical Study
Disease-Free Survival
Estrogens
Female
Humans
Kaplan-Meier Estimate
Ki-67 Antigen - metabolism
Lymphatic Metastasis
Medical prognosis
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local - metabolism
Neoplasm Recurrence, Local - prevention & control
Progesterone
Proportional Hazards Models
Receptors, Estrogen - metabolism
Receptors, Progesterone - metabolism
Tumor Suppressor Protein p53 - metabolism
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Zusammenfassung:Background: Breast cancer is associated with a relatively good prognosis. Prognostic factors examined to date are related to early recurrence while those related to late recurrence and their countermeasures remain unclear. Therefore, we examined the factors related to late recurrence. Patients and Methods: From January 1980 to August 2012, 4,774 patients who underwent primary treatment and estrogen (ER) and progesterone receptor (PgR) assessment were enrolled in this study. The patients were divided into two groups, those with a follow-up period
ISSN:0030-2414
1423-0232
DOI:10.1159/000353099