ChemInform Abstract: Enantioselective Synthesis of 2-Substituted and 3-Substituted Piperidines Through a Bromoaminocyclization Process

ChemInform Abstract: Enantioselective Synthesis of 2-Substituted and 3-Substituted Piperidines Through a Bromoaminocyclization Process

The catalytic enantioselective bromocyclization of olefinic amides (I) using quinine‐derived amino‐thiocarbamates as catalyst results in the formation of enantioenriched 2‐substituted 3‐bromopiperidines (II).

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ChemInform 2013-09, Vol.44 (38), p.no-no
Hauptverfasser: Zhou, Ling, Tay, Daniel Weiliang, Chen, Jie, Leung, Gulice Yiu Chung, Yeung, Ying-Yeung
Format: Artikel
Sprache:eng
Schlagworte:
diastereoselective syntheses
diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism)
enantioselective syntheses (incl. cis/trans-isomerism)
pyridine derivatives
rearrangements
ring closure reactions
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The catalytic enantioselective bromocyclization of olefinic amides (I) using quinine‐derived amino‐thiocarbamates as catalyst results in the formation of enantioenriched 2‐substituted 3‐bromopiperidines (II).
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201338148