Assessing tablet-sticking propensity
The effect of tableting lubricant was studied for blends containing either Ibuprofen or spray-dried mannitol with various levels of magnesium stéarate, As expected from tableting experience, the spray-dried mannitol had a lower absolute sticking propensity relative to Ibuprofen. But, interestingly,...
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Veröffentlicht in: | Pharmaceutical technology Europe 2012-01, Vol.24 (1), p.31 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The effect of tableting lubricant was studied for blends containing either Ibuprofen or spray-dried mannitol with various levels of magnesium stéarate, As expected from tableting experience, the spray-dried mannitol had a lower absolute sticking propensity relative to Ibuprofen. But, interestingly, opposite trends were observed for the mannitol versus the Ibuprofen formulations with various lubricant levels. |
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ISSN: | 1753-7967 |