Structure of Trimetazidine
The title compound is an antianginal agent. The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the...
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| Veröffentlicht in: | Analytical Sciences ; X-ray Structure and Analysis Online 2005, Vol.21, pp.x3-x4 |
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| container_title | Analytical Sciences ; X-ray Structure and Analysis Online |
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| creator | TANAKA, Rumiko HARAMURA, Masayuki TANAKA, Akito HIRAYAMA, Noriaki |
| description | The title compound is an antianginal agent. The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the least-squares planes of the piperazine and phenyl rings is 60.3(6)°. The methylene carbon atom bonded to the phenyl ring is significantly deviated from the plane of the phenyl ring. |
| doi_str_mv | 10.2116/analscix.21.x3 |
| format | Article |
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The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the least-squares planes of the piperazine and phenyl rings is 60.3(6)°. 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The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the least-squares planes of the piperazine and phenyl rings is 60.3(6)°. 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| title | Structure of Trimetazidine |
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