Structure of Trimetazidine
The title compound is an antianginal agent. The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the...
Gespeichert in:
| Veröffentlicht in: | Analytical Sciences ; X-ray Structure and Analysis Online 2005, Vol.21, pp.x3-x4 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The title compound is an antianginal agent. The crystal, C14H22N2O3·2HCl·1/2H2O, belongs to space group P21/a with cell dimensions of a = 13.139(6), b = 7.452(5), c = 17.991(8)Å, β = 93.20(4)°. The final R value is 0.081. The piperazine ring takes a chair conformation. The dihedral angle between the least-squares planes of the piperazine and phenyl rings is 60.3(6)°. The methylene carbon atom bonded to the phenyl ring is significantly deviated from the plane of the phenyl ring. |
|---|---|
| ISSN: | 1348-2238 1348-2238 1883-3578 |
| DOI: | 10.2116/analscix.21.x3 |