ChemInform Abstract: Synthesis, Characterization and in vitro Anticancer Evaluation of Novel 1,2,4-Triazolin-3-one Derivatives

ChemInform Abstract: Synthesis, Characterization and in vitro Anticancer Evaluation of Novel 1,2,4-Triazolin-3-one Derivatives

The triazolinone derivative (IIIf), the most active triazole among the title compounds, shows nearly 50--99% growth inhibition of various tumor cell lines, even at micromolar concentrations. [PUBLICATION ABSTRACT]

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Veröffentlicht in:ChemInform 2013-08, Vol.44 (33), p.no-no
Hauptverfasser: Kattimani, Pramod P., Kamble, Ravindra R., Kariduraganavar, Mahadevappa Y., Dorababu, Atukuri, Hunnur, Raveendra K.
Format: Artikel
Sprache:eng
Schlagworte:
anticancer activity
anticarcinogenic activity
anticarcinogenic activity, anticancer activity
triazole derivatives
Tumors
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Zusammenfassung:The triazolinone derivative (IIIf), the most active triazole among the title compounds, shows nearly 50--99% growth inhibition of various tumor cell lines, even at micromolar concentrations. [PUBLICATION ABSTRACT]
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201333153