Clozapine-Induced Restless Legs Syndrome Treated With Aripiprazole
Case Report "Ms. M," a 34-year-old woman with a 12-year history of treatment-resistant paranoid schizophrenia, having auditory hallucinations and multiple delusions, had poor response to adequate trials of haloperidol, risperidone, and injection fluphenazine. Because of treatment nonrespon...
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Veröffentlicht in: | The journal of neuropsychiatry and clinical neurosciences 2013-04, Vol.25 (2), p.E62-E63 |
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creator | Raveendranathan, Dhanya Shiva, Lakshmi Venkatasubramanian, Ganesan Rao, Mukund G Varambally, Shivarama Gangadhar, Bangalore N |
description | Case Report "Ms. M," a 34-year-old woman with a 12-year history of treatment-resistant paranoid schizophrenia, having auditory hallucinations and multiple delusions, had poor response to adequate trials of haloperidol, risperidone, and injection fluphenazine. Because of treatment nonresponse, she was started on clozapine, which was increased to 200 mg. Aripiprazole also had the added benefit of having a synergistic effect with clozapine,11 which enabled in improvement in the psychotic symptoms and enabled further increase in clozapine dosage, as well. [...]in antipsychotic-induced RLS, aripiprazole could be considered, as it would also have an added antipsychotic effect and, in a case like this, wherein the antipsychotic could not be stopped, as the patient was a nonresponder, and the psychotic symptoms were very severe. |
doi_str_mv | 10.1176/appi.neuropsych.12050128 |
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[...]in antipsychotic-induced RLS, aripiprazole could be considered, as it would also have an added antipsychotic effect and, in a case like this, wherein the antipsychotic could not be stopped, as the patient was a nonresponder, and the psychotic symptoms were very severe.</description><subject>Adult</subject><subject>Antipsychotic Agents - therapeutic use</subject><subject>Aripiprazole</subject><subject>Clozapine - adverse effects</subject><subject>Dopamine</subject><subject>Drug dosages</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Piperazines - therapeutic use</subject><subject>Psychotropic drugs</subject><subject>Quinolones - therapeutic use</subject><subject>Restless legs syndrome</subject><subject>Restless Legs Syndrome - drug therapy</subject><subject>Restless Legs Syndrome - etiology</subject><subject>Schizophrenia, Paranoid - complications</subject><subject>Schizophrenia, Paranoid - drug therapy</subject><issn>0895-0172</issn><issn>1545-7222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9PwjAUxxujEUT_BbPE87Dt1m47IvEHCYmJYjw2XfsqI2Or7XaAv94iIEdP7_C-P977IBQRPCYk4_fS2mrcQO9a6zdqOSYUM0xofoaGhKUsziil52iI84LFmGR0gK68X2GMacLTSzQII-c4I0P0MK3brbRVA_Gs0b0CHb2B72rwPprDl4_eN4127RqihQPZhfVn1S2jiatsZZ3ctjVcowsjaw83hzlCH0-Pi-lLPH99nk0n81gmjHdxqlRq0qzEClMOtExBG65URg0ucEGkpLkyZVoCzk1miNTKKIqB6wIgAaOTEbrb51rXfvfhSLFqe9eESkHCPywveMGCKt-rlGu9d2CEddVauo0gWOzgiR08cYInjvCC9fZQ0Jdr0H_GI60gYHvBb8Sp_b_gH4Gtg3s</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>Raveendranathan, Dhanya</creator><creator>Shiva, Lakshmi</creator><creator>Venkatasubramanian, Ganesan</creator><creator>Rao, Mukund G</creator><creator>Varambally, Shivarama</creator><creator>Gangadhar, Bangalore N</creator><general>American Psychiatric Association</general><general>American Psychiatric Publishing, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope></search><sort><creationdate>20130401</creationdate><title>Clozapine-Induced Restless Legs Syndrome Treated With Aripiprazole</title><author>Raveendranathan, Dhanya ; 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subjects | Adult Antipsychotic Agents - therapeutic use Aripiprazole Clozapine - adverse effects Dopamine Drug dosages Drug therapy Female Humans Piperazines - therapeutic use Psychotropic drugs Quinolones - therapeutic use Restless legs syndrome Restless Legs Syndrome - drug therapy Restless Legs Syndrome - etiology Schizophrenia, Paranoid - complications Schizophrenia, Paranoid - drug therapy |
title | Clozapine-Induced Restless Legs Syndrome Treated With Aripiprazole |
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