Cancer metabolism in breadth and depth

Recent advances in understanding the altered metabolism of tumor cells are yielding new therapeutic leads.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature biotechnology 2013-06, Vol.31 (6), p.505-507
Hauptverfasser:	Chun, Matthew G H, Shaw, Reuben J
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/2327 631/67/68 Agriculture Animals Benzeneacetamides - pharmacology Bioinformatics Biomedical Engineering/Biotechnology Biomedicine Biotechnology Cancer therapies Cell Differentiation Cell Transformation, Neoplastic - metabolism Enzyme Inhibitors - pharmacology Glioma - enzymology Glioma - pathology Glutamine - metabolism Hematopoiesis - drug effects Humans Imidazoles - pharmacology Isocitrate Dehydrogenase - antagonists & inhibitors Isocitrate Dehydrogenase - genetics Leukemia, Myeloid, Acute - enzymology Life Sciences Metabolic Networks and Pathways - genetics Metabolism Neoplasms - metabolism news-and-views Oncogene Protein p21(ras) - metabolism Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Phenylurea Compounds - pharmacology Proto-Oncogene Proteins - metabolism R&D ras Proteins - metabolism Research & development Sulfonamides - pharmacology Tumors
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Beschreibung
Zusammenfassung:	Recent advances in understanding the altered metabolism of tumor cells are yielding new therapeutic leads.
ISSN:	1087-0156 1546-1696
DOI:	10.1038/nbt.2611