Propargyl Anthranilate Derivatives and Their Application in the Synthesis of Rings Containing 1,2,3-Triazolo Motifs

Propargyl anthranilate, a simple and less studied molecule with several reactive sites, is widely applicable in organic synthesis. An optimized synthesis of this compound and its derivatives and the preparation of azide derivatives are described. The optimized process of the known intramolecular cyclization is described, and the unknown intermolecular cyclizations of these azido derivatives and formation of a macrocycle are discussed.