High-Throughput Label-Free Detection Using a Gold Nanoslit Array With 2-D Spectral Images and Spectral Integration Methods
We fabricated gold nanoslit arrays and experimentally compared the sensing capabilities using the single-polarization and multipolarization spectral integration methods. The signal-to-noise ratio and refractive index detection limit using the multipolarization method were increased to three times la...
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Veröffentlicht in: | IEEE journal of selected topics in quantum electronics 2013-05, Vol.19 (3), p.4800407-4800407 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | We fabricated gold nanoslit arrays and experimentally compared the sensing capabilities using the single-polarization and multipolarization spectral integration methods. The signal-to-noise ratio and refractive index detection limit using the multipolarization method were increased to three times larger than the simple integration method. Combining 2-D spectral images and the spectral integration method, we demonstrated real time and multiple detections of 30-nm-gold nanoparticles. The detection limit of the system is down to 0.147 particles/μm 2 . |
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ISSN: | 1077-260X 1558-4542 |
DOI: | 10.1109/JSTQE.2012.2234444 |