A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones

A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones

A simple and efficient approach to synthesize novel polysubstituted quinazolin‐4(3H)‐ones has been developed, and the key step is a sequential procedure involved iron‐mediated reduction and acid‐catalytic cyclization. The present method provides a convenient and practical strategy for the synthesis...

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Veröffentlicht in:Journal of heterocyclic chemistry 2013-01, Vol.50 (1), p.169-174
Hauptverfasser: Xin, Minhang, Gao, Ying, Xiang, Hua, Chen, Dong, He, Yi, You, Qidong
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container_issue 1
container_start_page 169
container_title Journal of heterocyclic chemistry
container_volume 50
creator Xin, Minhang
Gao, Ying
Xiang, Hua
Chen, Dong
He, Yi
You, Qidong
description A simple and efficient approach to synthesize novel polysubstituted quinazolin‐4(3H)‐ones has been developed, and the key step is a sequential procedure involved iron‐mediated reduction and acid‐catalytic cyclization. The present method provides a convenient and practical strategy for the synthesis of quinazolin‐4(3H)‐one derivatives.
doi_str_mv 10.1002/jhet.1001
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title A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones
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