A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones

A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones

A simple and efficient approach to synthesize novel polysubstituted quinazolin‐4(3H)‐ones has been developed, and the key step is a sequential procedure involved iron‐mediated reduction and acid‐catalytic cyclization. The present method provides a convenient and practical strategy for the synthesis...

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Veröffentlicht in:Journal of heterocyclic chemistry 2013-01, Vol.50 (1), p.169-174
Hauptverfasser: Xin, Minhang, Gao, Ying, Xiang, Hua, Chen, Dong, He, Yi, You, Qidong
Format: Artikel
Sprache:eng
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Zusammenfassung:A simple and efficient approach to synthesize novel polysubstituted quinazolin‐4(3H)‐ones has been developed, and the key step is a sequential procedure involved iron‐mediated reduction and acid‐catalytic cyclization. The present method provides a convenient and practical strategy for the synthesis of quinazolin‐4(3H)‐one derivatives.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.1001