ChemInform Abstract: Synthesis and Antiviral Properties of Novel Tetracyclic Nucleoside Inhibitors of Hepatitis C NS5B Polymerase

ChemInform Abstract: Synthesis and Antiviral Properties of Novel Tetracyclic Nucleoside Inhibitors of Hepatitis C NS5B Polymerase

A series of 2′‐C‐methyl‐ribose nucleoside derivatives bearing a 7‐aryl and 7‐hetaryl substituted 7‐deaza‐adenine nucleobase is discovered.

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Bibliographische Detailangaben
Veröffentlicht in:ChemInform 2013-03, Vol.44 (11), p.no-no
Hauptverfasser: Di Francesco, M. Emilia, Avolio, Salvatore, Dessole, Gabriella, Koch, Uwe, Pompei, Marco, Pucci, Vincenzo, Rowley, Michael, Summa, Vincenzo
Format: Artikel
Sprache:eng
Schlagworte:
antiviral activity
nucleic acids
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Beschreibung
Zusammenfassung:A series of 2′‐C‐methyl‐ribose nucleoside derivatives bearing a 7‐aryl and 7‐hetaryl substituted 7‐deaza‐adenine nucleobase is discovered.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201311196