The Reversal of Anticholinergic Drug-Induced Delirium and Coma with Physostigmine

Although its use for this purpose is not well recognized, physostigmine provides an effective and safe treatment for delirium and coma caused by anticholinergic agents such as atropine, scopolamine, and hyoscyamine. The authors summarize the supporting evidence and outline a recommended procedure.

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Bibliographische Detailangaben
Veröffentlicht in:	The American journal of psychiatry 1971-02, Vol.127 (8), p.1050-1054
Hauptverfasser:	HEISER, JON F, GILLIN, JOHN C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atropa belladonna - adverse effects Atropine - adverse effects Coma - chemically induced Coma - drug therapy Delirium - chemically induced Delirium - drug therapy Humans Plants, Medicinal Plants, Toxic
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Beschreibung
Zusammenfassung:	Although its use for this purpose is not well recognized, physostigmine provides an effective and safe treatment for delirium and coma caused by anticholinergic agents such as atropine, scopolamine, and hyoscyamine. The authors summarize the supporting evidence and outline a recommended procedure.
ISSN:	0002-953X 1535-7228
DOI:	10.1176/ajp.127.8.1050