Nicotinic Acid Side Effects and Toxicity: A Review

The author reviews the literature on the possible toxicity of nicotinic acid, whose therapeutic value in the treatment of schizophrenia is still in dispute. While the drug appears to be relatively harmless, caution in prescribing it is advised, especially for women of childbearing age and for patien...

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Veröffentlicht in:	The American journal of psychiatry 1970-03, Vol.126 (9), p.1290-1296
1. Verfasser:	MOSHER, LOREN R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Animals Anxiety - chemically induced Arteriosclerosis - drug therapy Carbohydrate Metabolism Digestive System - drug effects Duodenal Ulcer - chemically induced Female Humans Hypothyroidism - chemically induced Liver - drug effects Nicotinic Acids - adverse effects Nicotinic Acids - toxicity Pregnancy Schizophrenia - drug therapy Skin - drug effects Uric Acid - blood
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Beschreibung
Zusammenfassung:	The author reviews the literature on the possible toxicity of nicotinic acid, whose therapeutic value in the treatment of schizophrenia is still in dispute. While the drug appears to be relatively harmless, caution in prescribing it is advised, especially for women of childbearing age and for patients with a history of ulcer, gout, diabetes, or liver disease.
ISSN:	0002-953X 1535-7228
DOI:	10.1176/ajp.126.9.1290