Smoking and Risk of Leukemia

The relation between tobacco use and leukemia was evaluated in a population-based case-control study of 578 white men with leukemia and 820 controls conducted in Iowa and Minnesota during 1981–1984. Risks were significantly elevated for all leukemia (odds ratio (OR) = 1.4) and chronic lymphocyte leu...

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Veröffentlicht in:	American journal of epidemiology 1992-04, Vol.135 (7), p.763-768
Hauptverfasser:	Morris Brown, Linda, Gibson, Robert, Blair, Aaron, Burmeister, Leon F., Schuman, Leonard M., Cantor, Kenneth P., Fraumeni, Joseph F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Case-Control Studies Humans leukemia Leukemia - epidemiology Leukemia - etiology Male Medical sciences Middle Aged Odds Ratio Plants, Toxic Risk Factors smoking Smoking - adverse effects tobacco Tobacco, Smokeless - adverse effects Tobacco, tobacco smoking Toxicology
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Beschreibung
Zusammenfassung:	The relation between tobacco use and leukemia was evaluated in a population-based case-control study of 578 white men with leukemia and 820 controls conducted in Iowa and Minnesota during 1981–1984. Risks were significantly elevated for all leukemia (odds ratio (OR) = 1.4) and chronic lymphocyte leukemia (OR = 1.6) for both tobacco users and cigarette smokers. There were significantly elevated risks for cigarette smokers of longest duration for all leukemia (OR = 1.6), chronic myelogenous leukemia (OR = 3.3), and chronic lymphocytic leukemia (OR = 1.6). Thus, the findings of this study provide additional support for an association between smoking and the risk of several types of leukemia. Am J Epidemiol 1992;135:763–8.
ISSN:	0002-9262 1476-6256
DOI:	10.1093/oxfordjournals.aje.a116362