Interleukin-24 Suppresses the Growth of Vascular Smooth Muscle Cells by Inhibiting H2O2-Induced Reactive Oxygen Species Production

Background/Aim: The abnormal growth of vascular smooth muscle cells (VSMCs) induced by reactive oxygen species (ROS) is considered a major pathogenic process in vascular diseases. Interleukin (IL)-24 specifically inhibits cancer cell growth through the induction of cell cycle arrest and apoptosis. H...

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Veröffentlicht in:Pharmacology 2012-11, Vol.90 (5-6), p.332-341
Hauptverfasser: Lee, Ki-Mo, Kang, Haeng-A., Park, Min, Lee, Hwa-Youn, Song, Min-Ji, Ko, Kisung, Oh, Jae-Wook, Kang, Hyung-Sik
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Sprache:eng
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