Effects of synthetic C-terminal fragment of interferon-2α on Daudi cells

Effects of synthetic C-terminal fragment of interferon-2α on Daudi cells

Synthetic fragment of human interferon-2α (124th–138th amino acid residue, laboratory code 2438) inhibits the growth of B lymphocytes (Daudi cell line) in a dose-dependent manner. Radiolabeled peptide 2438 binds to specific receptors on the cell surface and competes with interferon-2α for the common...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1997-04, Vol.123 (4), p.388-390
Hauptverfasser: Romashkova, Yu. A., Danilkovich, A. V., Valuiskikh, A. N., Pershina, V. V., Freze, K. B., Sukhikh, G. T.
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
Binding sites
Cell surface
Interferon
Lymphocytes B
Proteins
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Zusammenfassung:Synthetic fragment of human interferon-2α (124th–138th amino acid residue, laboratory code 2438) inhibits the growth of B lymphocytes (Daudi cell line) in a dose-dependent manner. Radiolabeled peptide 2438 binds to specific receptors on the cell surface and competes with interferon-2α for the common binding sites.
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02766195