Effect of ionizing radiation on the expression of transforming growth factor-[beta]

Experiments demonstrate the stimulation of transforming growth factor-β expression in porcine skin soon after ψ-irradiation in a dose of 64 Gy and in mouse macrophages after whole body irradiation in a dose of 4 Gy, which suggests the involvement of macrophages that produce transforming growth facto...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1998-11, Vol.126 (5), p.1113
Hauptverfasser: Zubova, S G, Crechet, F, Gault, N, Danilov, A O, Vozenin, M K, Lefaix, J L, Daburon, F, Martin, M, Okulov, V B
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Sprache:eng
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Zusammenfassung:Experiments demonstrate the stimulation of transforming growth factor-β expression in porcine skin soon after ψ-irradiation in a dose of 64 Gy and in mouse macrophages after whole body irradiation in a dose of 4 Gy, which suggests the involvement of macrophages that produce transforming growth factor-β during the early postirradiation period in the development of postirradiation fibrosis.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02447248