HDL-binding lipoproteins on human fetal hepatocytes
Two types of binding sites for high-density lipoproteins (K^sub d^=1 μg/ml and 20 μg/ml) were identified on human fetal hepatocytes and designated as P^sub 1^ and P^sub 2^. Ligand blotting has shown that P^sub 1^ site is protein with Mr 100 kD and P^sub 2^ site involves two proteins with Mr 105 and...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 1998-10, Vol.126 (4), p.1052-1055 |
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| container_title | Bulletin of experimental biology and medicine |
| container_volume | 126 |
| creator | Bocharov, A. V. Vishnyakova, T. G. Baranova, I. N. Repin, V. S. Kornyushin, M. A. Kask, L. N. Sukhikh, G. T. Blidchenko, Yu. A. Eremeeva, M. V. |
| description | Two types of binding sites for high-density lipoproteins (K^sub d^=1 μg/ml and 20 μg/ml) were identified on human fetal hepatocytes and designated as P^sub 1^ and P^sub 2^. Ligand blotting has shown that P^sub 1^ site is protein with Mr 100 kD and P^sub 2^ site involves two proteins with Mr 105 and 110 kD. P^sub 2^ proteins were not detected when incubation with ligands was shortened from 24 h to 30 min. Molecular weight and activity of P^sub 1^ did not change considerably after reduction of disulfide bonds.[PUBLICATION ABSTRACT] |
| doi_str_mv | 10.1007/BF02447319 |
| format | Article |
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| identifier | ISSN: 0007-4888 |
| ispartof | Bulletin of experimental biology and medicine, 1998-10, Vol.126 (4), p.1052-1055 |
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| language | eng |
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| subjects | Binding sites Proteins |
| title | HDL-binding lipoproteins on human fetal hepatocytes |
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