Role of transforming growth factor-[beta] in erythroid cell-mediated suppression of B-cell blastogenesis
Soluble products spontaneously secreted by murine nuclear erythroid cells directly suppress the proliferation of activated B-lymphocytes induced by bacterial lipopolysaccharides. Blocking of the transforming growth factor-β synthesis in nuclear erythroid cells by antisense oligonucleotides binding m...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 1997-11, Vol.124 (5), p.1107 |
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| container_issue | 5 |
| container_start_page | 1107 |
| container_title | Bulletin of experimental biology and medicine |
| container_volume | 124 |
| creator | Seledtsova, G V Seledtsov, V I Samarin, D M Taraban, V Ya Sennikov, S V Kashchenko, E A Kozlov, V A |
| description | Soluble products spontaneously secreted by murine nuclear erythroid cells directly suppress the proliferation of activated B-lymphocytes induced by bacterial lipopolysaccharides. Blocking of the transforming growth factor-β synthesis in nuclear erythroid cells by antisense oligonucleotides binding mRNA and blocking of this factor's functional activity by neutralizing antibodies were associated with a marked decrease in suppressor activity of the medium conditioned by nuclear erythroid cells.[PUBLICATION ABSTRACT] |
| doi_str_mv | 10.1007/BF02445675 |
| format | Article |
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| ispartof | Bulletin of experimental biology and medicine, 1997-11, Vol.124 (5), p.1107 |
| issn | 0007-4888 1573-8221 |
| language | eng |
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| source | Springer Nature - Complete Springer Journals |
| subjects | Cells |
| title | Role of transforming growth factor-[beta] in erythroid cell-mediated suppression of B-cell blastogenesis |
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