Extra-and intracellular collagen resorption by smooth muscle cells in postpartum uterine involution

Localization of cathepsin B in rat uterus during postpartum involution is studied using electron histochemical technique. High extracellular activity of cathepsin B and accumulation of products on the cytolemma of smooth muscle cells and adjacent collagen fibrils are revealed. These findings suggest...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1999-01, Vol.127 (1), p.96-98
Hauptverfasser: Ryvnyak, V. V., Gudumak, V. S., Rybakova, M. A., Grumeza, O. F., Pelin, A. V.
Format: Artikel
Sprache:eng
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Zusammenfassung:Localization of cathepsin B in rat uterus during postpartum involution is studied using electron histochemical technique. High extracellular activity of cathepsin B and accumulation of products on the cytolemma of smooth muscle cells and adjacent collagen fibrils are revealed. These findings suggest that smooth muscle cells participate in the extracellular collagen degradation via secretion of cathepsin B.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02432812