Titrated dose of drotrecogin alpha for liver transplant recipient

Drotrecogin alpha promotes anticoagulation by the inhibition of factors V and VIII, anti-inflammatory response is created through indirect tumor necrosis factor-alpha inhibition, and fibrinolysis is via inhibition of plasminogen activator inhibitor. [5] in a septic patient with intestinal obstruction. Because their patient could not tolerate the 24 μg/ kg/hr dose, 18 μg/kg/hr drotrecogin alpha was administered and that patient showed a favorable recovery.