ChemInform Abstract: Nickel-Catalyzed Enantioselective Cross-Couplings of Racemic Secondary Electrophiles that Bear an Oxygen Leaving Group

A variety of silyl‐substituted propargylic carbonates are coupled with arylzinc iodides in the presence of a nickel/chiral bis(oxazolinyl)pyridine catalyst to give the arylated alkynes with up to 93% enantioselectivity.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2012-07, Vol.43 (29), p.no-no
Hauptverfasser:	Oelke, Alexander J., Sun, Jianwei, Fu, Gregory C.
Format:	Artikel
Sprache:	eng
Schlagworte:	C-C bond formation diastereoselective syntheses diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) enantioselective syntheses (incl. cis/trans-isomerism) Nickel organo-silicon compounds Oxygen reactions of organo-metal compounds
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Beschreibung
Zusammenfassung:	A variety of silyl‐substituted propargylic carbonates are coupled with arylzinc iodides in the presence of a nickel/chiral bis(oxazolinyl)pyridine catalyst to give the arylated alkynes with up to 93% enantioselectivity.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201229023