ChemInform Abstract: Synthesis and in vitro EGFR (ErbB1) Tyrosine Kinase Inhibitory Activity of 4-N-Substituted 6-Aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines

Title compounds like (VIII) are synthesized and tested for their in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2012-04, Vol.43 (15), p.no-no
Hauptverfasser:	Kaspersen, Svein Jacob, Soerum, Christopher, Willassen, Veronica, Fuglseth, Erik, Kjoebli, Eli, Bjoerkoey, Geir, Sundby, Eirik, Hoff, Baard Helge
Format:	Artikel
Sprache:	eng
Schlagworte:	enzyme inhibiting activity fused pyrimidine derivatives Proteins ring closure reactions structure-activity relationship
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Title compounds like (VIII) are synthesized and tested for their in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201215166