ChemInform Abstract: Synthesis of the ABH Rings of Ecteinascidin 597 Using a Connective Pummerer-Type Cyclization

ChemInform Abstract: Synthesis of the ABH Rings of Ecteinascidin 597 Using a Connective Pummerer-Type Cyclization

A connective Pummerer-type cyclization involving a N-protected glyoxamide (I) and a cysteine derivative (II) is applied to an asymmetric synthesis of the protected ABH rings of ecteinascidin 597. [PUBLICATION ABSTRACT]

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Veröffentlicht in:ChemInform 2012-02, Vol.43 (7), p.no-no
Hauptverfasser: Smith, Laura H. S., Nguyen, Trung Thanh, Sneddon, Helen F., Procter, David J.
Format: Artikel
Sprache:eng
Schlagworte:
alkaloids
ring closure reactions
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Zusammenfassung:A connective Pummerer-type cyclization involving a N-protected glyoxamide (I) and a cysteine derivative (II) is applied to an asymmetric synthesis of the protected ABH rings of ecteinascidin 597. [PUBLICATION ABSTRACT]
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201207198