An Efficient Synthesis of Bibenzylic Oxygen Heterocycles

The first total syntheses of naturally occurring 6-methoxy-4-(2-phenylethyl)benzofuran (1) and 2,2-dimethyl-7-methoxy-5-(2-phenylethyl)chroman (2) and the non-natural 7-methoxy-5-(2-phenylethyl)chromen-2-one (3) are described from 3,5-dimethoxyphenylacetic acid in good yields.

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Veröffentlicht in:Journal of chemical research 2007-10, Vol.2007 (10), p.590-593
Hauptverfasser: Kumbhar, Virendra B., Joseph, Augustine R., Natu, Arun D., Kusurkar, Radhika S., Paradkar, Madhusudan V.
Format: Artikel
Sprache:eng
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Zusammenfassung:The first total syntheses of naturally occurring 6-methoxy-4-(2-phenylethyl)benzofuran (1) and 2,2-dimethyl-7-methoxy-5-(2-phenylethyl)chroman (2) and the non-natural 7-methoxy-5-(2-phenylethyl)chromen-2-one (3) are described from 3,5-dimethoxyphenylacetic acid in good yields.
ISSN:1747-5198
2047-6507
DOI:10.3184/030823407X256091