Granular cell tumour of the gastrocnemius muscle - case report

Granular cell tumour (GCT), also known as Abrikosoff's tumour, is a rare neuroectodermal neoplasm. GCT makes up 0.019-0.03% of all neoplasms, and it most commonly appears in black women aged 40-60. GCT may appear anywhere on the body, but the most common locations are soft tissues of the head and neck, which constitute over a half of the cases. In most cases the tumour is benign. The authors present a very rare case of GCT in the gastrocnemius muscle. Gross examination of cells with abundant eosinophilic cytoplasm, prominent granulation and positive immunochemistry for S-100 protein confirmed the diagnosis of GCT in the described case. Eight months after radical surgery of the lesion there were no features of local recurrence. It could be assumed that the first-choice treatment of GCT is surgery of the lesion with a wide margin of healthy tissues. One of the factors that could have triggered neoplastic transformation was a trauma that took place a few months before the tumour appeared.