Calming effect of orally administered [gamma]-aminobutyric acid in Shih Tzu dogs

The calming effects of [gamma]-aminobutyric acid (GABA) by oral administration were investigated in four adult Shih Tzu dogs. Three dosage levels (1, 2 and 4mg/kg body weight) and non-administration were tested by an increase and decrease method. Changes in activity (for 1.5h) and urinary cortisol l...

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Veröffentlicht in:Animal science journal 2012-12, Vol.83 (12), p.796
Hauptverfasser: UETAKE, Katsuji, OKUMOTO, Ayano, TANI, Noriko, GOTO, Akihiro, TANAKA, Toshio
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Sprache:eng
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Zusammenfassung:The calming effects of [gamma]-aminobutyric acid (GABA) by oral administration were investigated in four adult Shih Tzu dogs. Three dosage levels (1, 2 and 4mg/kg body weight) and non-administration were tested by an increase and decrease method. Changes in activity (for 1.5h) and urinary cortisol levels (pre-administration, 3 and 7h later) of dogs were monitored after administration. Without reference to dosage level, the mean times spent standing (P=0.06), sitting (P
ISSN:1344-3941
1740-0929
DOI:10.1111/j.1740-0929.2012.01024.x