Corrigendum: Enantioselective Oxidation of Aldehydes Catalyzed by Alcohol Dehydrogenase

Corrigendum: Enantioselective Oxidation of Aldehydes Catalyzed by Alcohol Dehydrogenase

Teaching old dogs new tricks: Alcohol dehydrogenases (ADHs) may be established redox biocatalysts but they still are good for a few surprises. ADHs can be used to oxidize aldehydes, and this was demonstrated by the oxidative dynamic kinetic resolution of profens. In the presence of a suitable cofact...

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Veröffentlicht in:Angewandte Chemie International Edition 2012-11, Vol.51 (48), p.9914
Hauptverfasser: Könst, Paul, Merkens, Hedda, Kara, Selin, Kochius, Svenja, Vogel, Andreas, Zuhse, Ralf, Holtmann, Dirk, Arends, Isabel W. C. E, Hollmann, Frank
Format: Artikel
Sprache:eng
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Zusammenfassung:Teaching old dogs new tricks: Alcohol dehydrogenases (ADHs) may be established redox biocatalysts but they still are good for a few surprises. ADHs can be used to oxidize aldehydes, and this was demonstrated by the oxidative dynamic kinetic resolution of profens. In the presence of a suitable cofactor regeneration system, this reaction can occur with high selectivity.
ISSN:1433-7851
1521-3773