Hemorheology and Erythrodieresis in Patients with Ischemic Heart Disease. Medical Plasmapheresis

It has been established that in patients with ischemic heart disease the viscosity of the blood plasma and the aggregation activity of erythrocytes are increased, which increases the degree of circulatory disturbances, decreases the acidic resistance of erythrocytes, and increases the level of free hemoglobin (enhanced erythrodieresis), with the result that the disseminated intravascular coagulation of blood is activated. Medical plasmapheresis, i.e., substitution of an isotonic solution for 30-40% of the circulating-plasma volume, improves the hemorheological indices and decreases the level of free hemoglobin in the blood without changing significantly the indices of acidic erythrograms.[PUBLICATION ABSTRACT]