Clotting disturbances in Trypanosoma evansi-infected cats

Coagulopathy in cats (Felis catus) parasitized by Trypanosoma evansi in both the initial and chronic phases of the disease has been investigated. To address this issue, seven animals were infected with 10⁸ trypomastigote forms each, and six were used as control. Animals were monitored for 56 days by...

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Veröffentlicht in:Comparative clinical pathology 2010-04, Vol.19 (2), p.207-210
Hauptverfasser: Da Silva, Aleksandro S, Wolkmer, Patrícia, Costa, Márcio M, Zanette, Régis A, Oliveira, Camila B, Gressler, Lucas T, Otto, Mateus A, Santurio, Janio M, Lopes, Sonia T. A, Monteiro, Silvia Gonzalez
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Sprache:eng
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Zusammenfassung:Coagulopathy in cats (Felis catus) parasitized by Trypanosoma evansi in both the initial and chronic phases of the disease has been investigated. To address this issue, seven animals were infected with 10⁸ trypomastigote forms each, and six were used as control. Animals were monitored for 56 days by examining daily blood smears. Blood samples for hematocrit, platelet counting, and fibrinogen levels were collect at 15-day intervals. Prothrombin time, activated partial thromboplastin time, and number of megakaryocytes were analyzed at days 14 and 42 post-inoculation. A decrease in hematocrit values and platelet counts and an increase in plasmatic fibrinogen concentration were observed in the infected cats (P 
ISSN:1618-5641
1618-565X
DOI:10.1007/s00580-009-0855-2