Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective S^sub N^Ar reactions
Issue Title: Peptides as Toxins/Defensins Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by S^sub N^Ar reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-...
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| Veröffentlicht in: | Amino acids 2011-01, Vol.40 (1), p.197 |
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| container_title | Amino acids |
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| creator | Gonçalves, Renato S Abdelnur, Patrícia V Santos, Vanessa G Simas, Rosineide C Eberlin, Marcos N Magalhães, Alviclér Pérez González, Eduardo R |
| description | Issue Title: Peptides as Toxins/Defensins Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by S^sub N^Ar reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-elimination S^sub N^Ar mechanism was confirmed by NMR and MS measurements.[PUBLICATION ABSTRACT] |
| doi_str_mv | 10.1007/s00726-010-0634-z |
| format | Article |
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| language | eng |
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| title | Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective S^sub N^Ar reactions |
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