Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption

Reports a case of massive ingestion of Panadol Osteo® with biphasic, prolonged absorption requiring extended treatment with N-acetylcysteine. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons At...

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Veröffentlicht in:	New Zealand medical journal 2009-08, Vol.122 (1300), p.64-71
1. Verfasser:	Graudins, Andis
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen - administration & dosage Acetaminophen - adverse effects Acetaminophen - pharmacokinetics Acetylcysteine - therapeutic use Aged Alanine Transaminase - blood Analgesics, Non-Narcotic - administration & dosage Analgesics, Non-Narcotic - adverse effects Analgesics, Non-Narcotic - pharmacokinetics Aspartate Aminotransferases - blood Delayed-Action Preparations Drug dosages Drug Overdose Drugs Emergency medical care Female Free Radical Scavengers - therapeutic use Humans Infusions, Intravenous Medicine Metabolites Overdosage Physiological effect
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Zusammenfassung:	Reports a case of massive ingestion of Panadol Osteo® with biphasic, prolonged absorption requiring extended treatment with N-acetylcysteine. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons Attribution 3.0 New Zealand Licence.
ISSN:	0028-8446 1175-8716 1175-8716