Transcriptional Response to GAA Deficiency in Mice and Humans

Transcriptional Response to GAA Deficiency in Mice and Humans

[...]though inflammatory infiltrate is not consistently observed in the muscles of either GAA knockout mice or Pompe patients, we observed substantial inductions of immune-related genes in both species.

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Veröffentlicht in:Clinical therapeutics 2011-06, Vol.33 (6), p.S25-S25
Hauptverfasser: Palermo, A, Palmer, R, So, K, Zhang, M, Richards, B, Shah, S, Finn, P, Oba-Shinjo, S, Pescatori, M, Marie, S, McVie-Wylie, A, Mattaliano, R, Pomponio, R, Madden, S, Klinger, K
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Sprache:eng
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Gene expression
Internal Medicine
Medical Education
Medical research
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container_end_page S25
container_issue 6
container_start_page S25
container_title Clinical therapeutics
container_volume 33
creator Palermo, A
Palmer, R
So, K
Zhang, M
Richards, B
Shah, S
Finn, P
Oba-Shinjo, S
Pescatori, M
Marie, S
McVie-Wylie, A
Mattaliano, R
Pomponio, R
Madden, S
Klinger, K
description [...]though inflammatory infiltrate is not consistently observed in the muscles of either GAA knockout mice or Pompe patients, we observed substantial inductions of immune-related genes in both species.
doi_str_mv 10.1016/j.clinthera.2011.05.066
format Article
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identifier ISSN: 0149-2918
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source Elsevier ScienceDirect Journals; ProQuest Central UK/Ireland
subjects Gene expression
Internal Medicine
Medical Education
Medical research
title Transcriptional Response to GAA Deficiency in Mice and Humans
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