An unusual case of dipropylene glycol toxicity

There is a disconnect in this case between the apparent lack of significant toxicity of DPG in animal testing and prior reports and this patient's severe toxicity. Because some of the pharmaceutical epidemic poisonings occurred as a result of DEG contamination of glycerin or propylene glycol, w...

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Veröffentlicht in:	The American journal of emergency medicine 2009, Vol.27 (1), p.122-123
Hauptverfasser:	Nelsen, Jamie, PharmD, Marraffa, Jeanna M., PharmD, DABAT, Stork, Christine M., PharmD, DABAT, Hodgman, Michael, MD, ACMT, Holland, Michael G., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Emergency Emergency medical care Health facilities Humans Nervous System Diseases - chemically induced Poisoning Propylene Glycol - poisoning Solvents - poisoning Toxicity
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	There is a disconnect in this case between the apparent lack of significant toxicity of DPG in animal testing and prior reports and this patient's severe toxicity. Because some of the pharmaceutical epidemic poisonings occurred as a result of DEG contamination of glycerin or propylene glycol, we wonder if this DPG-containing product was contaminated with DEG as well?
ISSN:	0735-6757 1532-8171
DOI:	10.1016/j.ajem.2008.09.008