Impact of intensity-modulated and image-guided radiotherapy on elderly patients undergoing chemoradiation for locally advanced head and neck cancer

Impact of intensity-modulated and image-guided radiotherapy on elderly patients undergoing chemoradiation for locally advanced head and neck cancer

Purpose In this work, the treatment tolerance of elderly patients (≥70 years) undergoing intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) and chemotherapy for locally advanced head and neck cancer was assessed. Patients and methods A retrospective review of 112 patients u...

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Veröffentlicht in:Strahlentherapie und Onkologie 2012-08, Vol.188 (8), p.677-685
Hauptverfasser: Nguyen, N.P., Vock, J., Chi, A., Vinh-Hung, V., Dutta, S., Ewell, L., Jang, S., Betz, M., Almeida, F., Miller, M., Davis, R., Sroka, T., Vo, R.P., Karlsson, U., Vos, P.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Age Factors
Aged
Aged, 80 and over
Arizona
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - therapy
Chemoradiotherapy
Combined Modality Therapy
Disease-Free Survival
Female
Follow-Up Studies
Head and Neck Neoplasms - mortality
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - therapy
Humans
Lymphatic Metastasis
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Staging
Oncology
Organs at Risk
Original Article
Otorhinolaryngologic Neoplasms - mortality
Otorhinolaryngologic Neoplasms - pathology
Otorhinolaryngologic Neoplasms - therapy
Radiation Injuries - etiology
Radiotherapy
Radiotherapy Planning, Computer-Assisted - methods
Radiotherapy, Computer-Assisted - methods
Radiotherapy, Intensity-Modulated - methods
Retrospective Studies
Squamous Cell Carcinoma of Head and Neck
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Zusammenfassung:Purpose In this work, the treatment tolerance of elderly patients (≥70 years) undergoing intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) and chemotherapy for locally advanced head and neck cancer was assessed. Patients and methods A retrospective review of 112 patients undergoing concurrent chemoradiation for locally advanced head and neck cancer was performed. Treatment toxicity, protocol violations, long-term complications, and survival were compared between 85 younger patients (
ISSN:0179-7158
1439-099X
DOI:10.1007/s00066-012-0125-0