P-395: Left atrial enlargement and left ventricular remodeling in patients with secondary arterial hypertension

Left atrial (LA) dilatation is the early sign of the development of hypertensive heart disease in patients with arterial hypertension (AH). The aim of the study was to determine the relation between LA dimension and the different types of left ventricular (LV) remodeling. This study population consisted of 63 untreated patients (BP>140 mm Hg.) with secondary arterial hypertension (SAH) of renal genesis (chronic pyelonephritis)- 38 males and 25 females, 42–64 years. All patients were examined by 2-D guided M-mode Echocardiography. LV mass index (LVMI), relative wall thickness (RWT), LA and aortic dimensions were determined. LVMI and RWT were calculated to determine LV geometry patterns. LA size was evaluated by calculating LA dimension, LA index (LA dimension/ body surface area) and LA/aortic diastolic diameter (ADD) ratio. In the patients with SAH LVMI was 137.4 ± 3.9 g/m2, RWT was 0.45 ± 0.01, ADD was 2.91 ±0.09 cm, LA dimension was 3.39 ± 1.0 cm and LA index was 1.82 ± 0.07 cm/m’b2 and LA/ADD ratio was 1.16 ±0.06. Normal geometry had 24(38.1%) patients with SAH, 18(28.6 %) had LV concentric remodeling, 11 (17.4%) patients with SAH had LV concentric hypertrophy and 10 (15.9 %) patients with SAH had LV eccentric hypertrophy. LA dimension was significantly greater in secondary hypertensive patients with LV concentric and eccentric hypertrophy compared to those with LV normal geometry and concentric remodeling (3.68 ±5.2 and 3.62 ±5.1 vs 3.27 ±3.4 vs ± 3.29 ±3.5 cm, P